e-Newsletter

To better serve the needs and interests of researchers who use drug metabolism and drug interaction assay tools, BD Biosciences is pleased to launch a new quarterly Newsletter - the ADME/Tox Solutions. You were selected to receive this quarterly newsletter based upon your areas of interest. Should you wish to review these or sign up for additional newsletters on different topics, please click here to update your profile.

Welcome to our first issue of ADME/Tox Solutions.

NEW BD Supersomes™ Human UDP-Glucuronosyltransferases Portfolio

BD has expanded its portfolio of human UDP-Glucuronosyltransferases to include human UGT2B10: an enzyme abundant in liver, and important for the glucuronidation of several tricyclic antidepressant drugs such as amitriptyline.
View Datasheet | Request a sample for evaluation

NEW Plateable Human CryoHepatocytes

BD Gentest™ plateable cryopreserved hepatocytes are pre-screened, application-specific products designed to save researchers time evaluating multiple lots. Each lot is characterized for transporter mediated uptake and biliary efflux activity, high metabolic activity for low clearance drugs, and enzyme induction.
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High Viability CryoHepatocyte Recovery Kit

The BD Gentest high viability cryohepatocyte recovery kit provides a high-viability, high-yield recovery medium optimized for a single centrifugation step as well as an optimized plating medium for high plating efficiency. Use it for purification of platable human cryohepatocytes.
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The most rapid path to sound decision making - BD Gentest^SM Contract Research Services

BD Biosciences’ validated assay methods combined with BIOCIUS’s RapidFire® high-throughput mass spectrometry technology provide researchers a high-quality, cost-effective inhibition screening service.
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Toolbox

Scientific Posters

Cryopreserved Hepatocytes

Datasheet: BD Gentest Plateable Human CryoHepatocytes

Datasheet: BD Gentest High Viability CryoHepatocyte Recovery Kit

Frequently Asked Questions: Hepatocytes

Application Note:
BD Matrigel™ Matrix Thin-Coat and BD Matrigel Matrix Overlay Improved CYP450 Activities in Human Cryopreserved Hepatocytes

BD Supersomes
Datasheet: BD Supersomes Human UDP glucuronosyltransferases Portfolio

Request a sample for evaluation

Contract Research Services
Brochure: In Vitro ADME discovery screening research services

Posters presented at ISSX in Atlanta,
Oct. 16 - 20, 2011

Characterization of ABC Transporters and SLC Transporters in Sandwich Cultured Human Cryopreserved Hepatocytes

Development of ex-vivo Drug Metabolizing Enzyme Assays in Domestic Shorthair Cat

Comparison of Digoxin Efflux Inhibition in Caco-2 and MDR1-LLC-PK1 Cell Monolayers

Events

January 26-27, 2012 - Brussels
7th Annual International Conference on Predictive Human Toxicity and ADME/Tox Studies

February 27-29, 2012 - Berlin
3rd International Clinically Relevant Drug Transporters

BD Biosciences, Erembodegem-Dorp 86, 9320 Erembodegem, Belgium
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